The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown. Our study showed that fully reprogrammed mature iPSCs or mouse embryonic stem...

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Bibliographic Details
Main Authors: Qidong Liu, Guiying Wang, Yao Lyu, Mingliang Bai, Zeyidan Jiapaer, Wenwen Jia, Tong Han, Rong Weng, Yiwei Yang, Yangyang Yu, Jiuhong Kang
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111830225X