MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway

MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway

Abstract Background Intervertebral disc degeneration (IDD) is a major contributor to back, neck, and radicular pain, and the treatment of IDD is costly and relatively ineffective. Dysregulation of microRNAs (miRNAs) has been reported to be involved in IDD. The purpose of our study is to illustrate t...

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Bibliographic Details
Main Authors: Qi Yang, Xiao-Peng Guo, Yan-Li Cheng, Yang Wang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Arthritis Research & Therapy
Subjects:
MicroRNA-143-5p
EEF2
AMPK signaling pathway
Nucleus pulposus cells
Differentiation
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13075-019-1863-5

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http://link.springer.com/article/10.1186/s13075-019-1863-5

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