Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores

Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body flu...

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Bibliographic Details
Main Authors: Nicole Stéphanie Galenkamp, Misha Soskine, Jos Hermans, Carsten Wloka, Giovanni Maglia
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06534-1