Integration of PEG 400 into a self-nanoemulsifying drug delivery system improves drug loading capacity and nasal mucosa permeability and prolongs the survival of rats with malignant brain tumors

Integration of PEG 400 into a self-nanoemulsifying drug delivery system improves drug loading capacity and nasal mucosa permeability and prolongs the survival of rats with malignant brain tumors

Yu-Shuan Chen,1–3 Yu-Han Chiu,3 Yuan-Sheng Li,3 En-Yi Lin,3,4 Dean-Kuo Hsieh,5 Chia-Hung Lee,3 Mao-Hsuan Huang,1 Hong-Meng Chuang,1 Shinn-Zong Lin,1,6 Horng-Jyh Harn,1,7,* Tzyy-Wen Chiou3,*1Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, Republic of China; 2Depa...

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Bibliographic Details
Main Authors: Chen YS, Chiu YH, Li YS, Lin EY, Hsieh DK, Lee CH, Huang MH, Chuang HM, Lin SZ, Harn HJ, Chiou TW
Format: Article
Language:English
Published: Dove Medical Press 2019-05-01
Series:International Journal of Nanomedicine
Subjects:
Glioblastoma
Polyethylene glycol 400
butylidenephthalide
loading capacity
permeability
intranasal administration
Online Access:https://www.dovepress.com/integration-of-peg-400-into-a-self-nanoemulsifying-drug-delivery-syste-peer-reviewed-article-IJN

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https://www.dovepress.com/integration-of-peg-400-into-a-self-nanoemulsifying-drug-delivery-syste-peer-reviewed-article-IJN

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