Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes

Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes

The purpose of this study was to determine the frequency of clinically actionable treatment-relevant germline pharmacogenomic variants in patients with cancer and assess the real-world clinical utility of universal screening using whole-exome sequencing in this population. Cancer patients underwent...

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Bibliographic Details
Main Authors: Megan L. Hutchcraft, Nan Lin, Shulin Zhang, Catherine Sears, Kyle Zacholski, Elizabeth A. Belcher, Eric B. Durbin, John L. Villano, Michael J. Cavnar, Susanne M. Arnold, Frederick R. Ueland, Jill M. Kolesar
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
pharmacogenomics
cancer
real word
irinotecan
5-fluorouracil
mercaptopurine
Online Access:https://www.mdpi.com/2072-6694/13/18/4524

Internet

https://www.mdpi.com/2072-6694/13/18/4524

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