Jiangzhi Granule attenuates non-alcoholic steatohepatitis by suppressing TNF/NFκB signaling pathway-a study based on network pharmacology

Jiangzhi Granule attenuates non-alcoholic steatohepatitis by suppressing TNF/NFκB signaling pathway-a study based on network pharmacology

Jiangzhi Granule is a commonly used traditional Chinese medicine for treating non-alcoholic fatty liver disease. However, its key ingredients and underlying mechanisms for attenuating nonalcoholic steatohepatitis (NASH) remain unclear. To address this issue, UPLC-TOF-MS based chemical profiling, net...

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Bibliographic Details
Main Authors: Wenjun Zhou, Ziye Zhu, Xiaoli Xiao, Chunlin Li, Li Zhang, Yanqi Dang, Guangbo Ge, Guang Ji, Mingzhe Zhu, Hongxi Xu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Jiangzhi Granule
Nonalcoholic steatohepatitis
TNF/NFκB signaling
Macrophage M1-type polarization
Network pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221009653

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http://www.sciencedirect.com/science/article/pii/S0753332221009653

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