Origin of the nuclear proteome on the basis of pre-existing nuclear localization signals in prokaryotic proteins

Abstract Background The origin of the selective nuclear protein import machinery, which consists of nuclear pore complexes and adaptor molecules interacting with the nuclear localization signals (NLSs) of cargo molecules, is one of the most important events in the evolution of eukaryotic cells. How...

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Bibliographic Details
Main Authors: Olga M. Lisitsyna, Margarita A. Kurnaeva, Eugene A. Arifulin, Maria Y. Shubina, Yana R. Musinova, Andrey A. Mironov, Eugene V. Sheval
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Biology Direct
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13062-020-00263-6