Origin of the nuclear proteome on the basis of pre-existing nuclear localization signals in prokaryotic proteins
Abstract Background The origin of the selective nuclear protein import machinery, which consists of nuclear pore complexes and adaptor molecules interacting with the nuclear localization signals (NLSs) of cargo molecules, is one of the most important events in the evolution of eukaryotic cells. How...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Biology Direct |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13062-020-00263-6 |