Separation of Coiled-Coil Structures in Lamin A/C is Required for the Elongation of the Filament

Intermediate filaments (IFs) commonly have structural elements of a central α-helical coiled-coil domain consisting of coil 1a, coil 1b, coil 2, and their flanking linkers. Recently, the crystal structure of a long lamin A/C fragment was determined and showed detailed features of a tetrameric unit....

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Bibliographic Details
Main Authors: Jinsook Ahn, Soyeon Jeong, So-mi Kang, Inseong Jo, Bum-Joon Park, Nam-Chul Ha
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/1/55