Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury.

Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury.

Traumatic brain injury (TBI) is an established risk factor for the development of Alzheimer's disease (AD). Here the effects of severe penetrating TBI on APP and tau cleavage processing were investigated in a rodent model of penetrating ballistic-like brain injury (PBBI). PBBI was induced by st...

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Bibliographic Details
Main Authors: Casandra M Cartagena, Andrea Mountney, Hye Hwang, Adam Swiercz, Zoe Rammelkamp, Angela M Boutte, Deborah A Shear, Frank C Tortella, Kara E Schmid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4948774?pdf=render

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http://europepmc.org/articles/PMC4948774?pdf=render

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