MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells

MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells

Abstract Background Among older adults, arterial aging is the major factor contributing to increased risk for cardiovascular disease–related morbidity and mortality. The chronic vascular inflammation that accompanies aging causes diffuse intimal–medial thickening of the arterial wall, thus increasin...

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Bibliographic Details
Main Authors: Hou-Yu Chiang, Pao-Hsien Chu, Ting-Hein Lee
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Biomedical Science
Subjects:
Arterial aging
MFG-E8
NF-κB
Cell adhesion molecules
Vascular smooth muscle cells
Online Access:http://link.springer.com/article/10.1186/s12929-019-0559-0

Internet

http://link.springer.com/article/10.1186/s12929-019-0559-0

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