The modular organization of domain structures: insights into protein-protein binding.
Domains are the building blocks of proteins and play a crucial role in protein-protein interactions. Here, we propose a new approach for the analysis and prediction of domain-domain interfaces. Our method, which relies on the representation of domains as residue-interacting networks, finds an optima...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2134966?pdf=render |