The modular organization of domain structures: insights into protein-protein binding.

Domains are the building blocks of proteins and play a crucial role in protein-protein interactions. Here, we propose a new approach for the analysis and prediction of domain-domain interfaces. Our method, which relies on the representation of domains as residue-interacting networks, finds an optima...

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Bibliographic Details
Main Authors: Antonio del Sol, Pablo Carbonell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2134966?pdf=render