Four-Factor Prothrombin Complex Concentrate Reduces Time to Procedure in Vitamin K Antagonist-Treated Patients Experiencing Gastrointestinal Bleeding: A Post Hoc Analysis of Two Randomized Controlled Trials

Introduction. To investigate the impact of a 4-factor prothrombin complex concentrate (4F-PCC [Beriplex®/Kcentra®]) versus plasma on “time to procedure” in patients with acute/severe gastrointestinal bleeding requiring rapid vitamin K antagonist (VKA) reversal prior to invasive procedure. Methods. A...

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Bibliographic Details
Main Authors: Majed A. Refaai, Truptesh H. Kothari, Shana Straub, Jacob Falcon, Ravi Sarode, Joshua N. Goldstein, Andres Brainsky, Laurel Omert, Martin L. Lee, Truman J. Milling
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2017/8024356