Unliganded estrogen receptor alpha promotes PC12 survival during serum starvation.

Many studies have reported proliferative, differentiating or protective effects of estradiol, notably through estrogen receptor alpha (ERα). On the contrary, the ligand-independent action of ERα is currently poorly documented notably in cell protection. The stable transfection of wild type, substitu...

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Bibliographic Details
Main Authors: François Ferriere, Denis Habauzit, Farzad Pakdel, Christian Saligaut, Gilles Flouriot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692477?pdf=render