Acquisition, maintenance and adaptation of invasion inhibitory antibodies against Plasmodium falciparum invasion ligands involved in immune evasion.

Erythrocyte-binding antigens (EBAs) and P. falciparum reticulocyte-binding homologue proteins (PfRhs) are two important protein families that can vary in expression and utilization by P. falciparum to evade inhibitory antibodies. We evaluated antibodies at repeated time-points among individuals livi...

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Main Authors: Muyideen K Tijani, Oluwatoyin A Babalola, Alex B Odaibo, Chiaka I Anumudu, Adanze O Asinobi, Olajumoke A Morenikeji, Michael C Asuzu, Christine Langer, Linda Reiling, James G Beeson, Mats Wahlgren, Roseangela I Nwuba, Kristina E M Persson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5546579?pdf=render