Microparticles mediate the intercellular regulation of microRNA-503 and proline-rich tyrosine kinase 2 to alter the migration and invasion capacity of breast cancer cells.

Microparticles mediate the intercellular regulation of microRNA-503 and proline-rich tyrosine kinase 2 to alter the migration and invasion capacity of breast cancer cells.

The successful treatment of cancer is hampered by drug resistance and metastasis. While these two obstacles were once considered separately, recent evidence associates resistance with an enhanced metastatic capacity. However, the underlying mechanisms remain undefined. We previously described the in...

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Bibliographic Details
Main Authors: Joyce eGong, Cheuk Fai Luk, Ritu eJaiswal, Mary eBebawy
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Oncology
Subjects:
Microarray
microRNA
breast cancer
metastasis
multidrug resistance
microparticles
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00220/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00220/full

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