Lobe specific Ca2+-calmodulin nano-domain in neuronal spines: a single molecule level analysis.
Calmodulin (CaM) is a ubiquitous Ca(2+) buffer and second messenger that affects cellular function as diverse as cardiac excitability, synaptic plasticity, and gene transcription. In CA1 pyramidal neurons, CaM regulates two opposing Ca(2+)-dependent processes that underlie memory formation: long-ter...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-11-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2978734?pdf=render |