Lobe specific Ca2+-calmodulin nano-domain in neuronal spines: a single molecule level analysis.

Calmodulin (CaM) is a ubiquitous Ca(2+) buffer and second messenger that affects cellular function as diverse as cardiac excitability, synaptic plasticity, and gene transcription. In CA1 pyramidal neurons, CaM regulates two opposing Ca(2+)-dependent processes that underlie memory formation: long-ter...

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Bibliographic Details
Main Authors: Yoshihisa Kubota, M Neal Waxham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2978734?pdf=render