2i, or Not 2i: The Soliloquy of Nanog-Negative Mouse Embryonic Stem Cells

In this issue of Stem Cell Reports, Hastreiter et al. (2018) use continuous time-lapse imaging of mouse embryonic stem cells to investigate how the inhibition of GSK3b and MEK/ERK (2i) leads to homogeneous expression of the transcription factor Nanog. They show that both induction of Nanog expressio...

Full description

Bibliographic Details
Main Author: Pablo Navarro
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118302807