USE OF PYRIDOXINE TO INCREASE ANTICACNER ACTIVITY OF METHIONINE-GAMMA-LYASE IN MURINE CANCER MODELS

USE OF PYRIDOXINE TO INCREASE ANTICACNER ACTIVITY OF METHIONINE-GAMMA-LYASE IN MURINE CANCER MODELS

We presented results of monotherapy and combination therapy of transplantable murine tumor models using methionine-gamma-lyase (MGL) and pyridoxine hydrochloride. We studied MGL from Clostridium sporogenes and Citrobacter freundii. We used Lewis lung carcinoma (LLC), melanoma B16, leukemias P388 and...

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Bibliographic Details
Main Authors:	D. Zh. Davydov, Е. А. Morozova, М. V. Komarova, N. V. Anufrieva, G. B. Zavilgelsky, I. V. Manukhov, T. V. Demidkina, Е. М. Treshchalina, V. S. Pokrovsky
Format:	Article
Language:	Russian
Published:	Tomsk National Research Medical Center of the Russian Academy of Sciences 2017-11-01
Series:	Sibirskij Onkologičeskij Žurnal
Subjects:	methionine-gamma-lyase mgl pyridoxine anticancer enzyme lewis lung carcinoma b16 melanoma p388 leukemia l5178y
Online Access:	https://www.siboncoj.ru/jour/article/view/610

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