USE OF PYRIDOXINE TO INCREASE ANTICACNER ACTIVITY OF METHIONINE-GAMMA-LYASE IN MURINE CANCER MODELS

USE OF PYRIDOXINE TO INCREASE ANTICACNER ACTIVITY OF METHIONINE-GAMMA-LYASE IN MURINE CANCER MODELS

We presented results of monotherapy and combination therapy of transplantable murine tumor models using methionine-gamma-lyase (MGL) and pyridoxine hydrochloride. We studied MGL from Clostridium sporogenes and Citrobacter freundii. We used Lewis lung carcinoma (LLC), melanoma B16, leukemias P388 and...

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Bibliographic Details
Main Authors: D. Zh. Davydov, Е. А. Morozova, М. V. Komarova, N. V. Anufrieva, G. B. Zavilgelsky, I. V. Manukhov, T. V. Demidkina, Е. М. Treshchalina, V. S. Pokrovsky
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2017-11-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
methionine-gamma-lyase
mgl
pyridoxine
anticancer enzyme
lewis lung carcinoma
b16 melanoma
p388 leukemia
l5178y
Online Access:https://www.siboncoj.ru/jour/article/view/610

Internet

https://www.siboncoj.ru/jour/article/view/610

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