Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction

Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction

Cardiovascular complications are the most prevalent cause of morbidity and mortality in diabetic patients. Metformin is currently the first-line blood glucose-lowering agent with potential relevance to cardiovascular diseases. However, the underpinning mechanisms of action remain elusive. Here, we r...

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Bibliographic Details
Main Authors: Halyna Loi, Frederic Boal, Helene Tronchere, Mathieu Cinato, Solomiia Kramar, Oleksandra Oleshchuk, Mykhaylo Korda, Oksana Kunduzova
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Pharmacology
Subjects:
metformin
myocardial infarction
hypertrophy
apoptosis
cardiac remodeling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00154/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00154/full

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