Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression

Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression

Abstract Background Spinal muscular atrophy is an inherited neurodegenerative disease caused by insufficient levels of the survival motor neuron (SMN) protein. Recently approved treatments aimed at increasing SMN protein levels have dramatically improved patient survival and have altered the disease...

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Bibliographic Details
Main Authors: Nikki M. McCormack, Eric Villalón, Coralie Viollet, Anthony R. Soltis, Clifton L. Dalgard, Christian L. Lorson, Barrington G. Burnett
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Myoblast
Muscle
Spinal muscular atrophy
Myomaker
Myomixer
Online Access:https://doi.org/10.1002/jcsm.12740

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