Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression
Abstract Background Spinal muscular atrophy is an inherited neurodegenerative disease caused by insufficient levels of the survival motor neuron (SMN) protein. Recently approved treatments aimed at increasing SMN protein levels have dramatically improved patient survival and have altered the disease...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-08-01
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Series: | Journal of Cachexia, Sarcopenia and Muscle |
Subjects: | |
Online Access: | https://doi.org/10.1002/jcsm.12740 |