Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

The GHR signaling pathway plays important roles in growth, metabolism, cell cycle control, immunity, homeostatic processes, and chemoresistance via both the JAK/STAT and the SRC pathways. Dysregulation of GHR signaling is associated with various diseases and chronic conditions such as acromegaly, ca...

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Bibliographic Details
Main Authors: Ger J. Strous, Ana Da Silva Almeida, Joyce Putters, Julia Schantl, Magdalena Sedek, Johan A. Slotman, Tobias Nespital, Gerco C. Hassink, Jan A. Mol
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
aging
cancer
ubiquitin
endocytosis
GH/IGF-1 axis
GH sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.597573/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.597573/full

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