Similar incidence of DNA damage response pathway alterations between clinically localized and metastatic prostate cancer
Abstract Background In this era of precision medicine, the DNA damage response (DDR) pathway has been shown to be a viable target of intervention in metastatic castration-resistant prostate cancer (CRPC) as approximately one-third of CRPC patients harbor DDR pathway mutations. To determine whether D...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
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Series: | BMC Urology |
Online Access: | http://link.springer.com/article/10.1186/s12894-019-0453-9 |