Similar incidence of DNA damage response pathway alterations between clinically localized and metastatic prostate cancer

Abstract Background In this era of precision medicine, the DNA damage response (DDR) pathway has been shown to be a viable target of intervention in metastatic castration-resistant prostate cancer (CRPC) as approximately one-third of CRPC patients harbor DDR pathway mutations. To determine whether D...

Full description

Bibliographic Details
Main Authors: Isaac E. Kim, Sinae Kim, Arnav Srivastava, Biren Saraiya, Tina Mayer, Wun-Jae Kim, Isaac Yi Kim
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Urology
Online Access:http://link.springer.com/article/10.1186/s12894-019-0453-9