The Role of N-Acetylcysteine Supplementation on the Oxidative Stress Levels, Genotoxicity and Lineage Commitment Potential of Ex Vivo Murine Haematopoietic Stem/Progenitor Cells

The Role of N-Acetylcysteine Supplementation on the Oxidative Stress Levels, Genotoxicity and Lineage Commitment Potential of Ex Vivo Murine Haematopoietic Stem/Progenitor Cells

Objectives: The ex vivo maintenance of haematopoietic stem/progenitor cells (HSPCs) is crucial to ensure a sufficient supply of functional cells for research or therapeutic applications. However, when exposed to reactive oxygen species (ROS) in a normoxic microenvironment, HSPCs exhibit genomic inst...

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Bibliographic Details
Main Authors: Zariyantey A. Hamid, Hui Y. Tan, Paik W. Chow, Khairul A. W. Harto, Chin Y. Chan, Jamaludin Mohamed
Format: Article
Language:English
Published: Sultan Qaboos University 2018-09-01
Series:Sultan Qaboos University Medical Journal
Online Access:https://journals.squ.edu.om/index.php/squmj/article/view/2708

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https://journals.squ.edu.om/index.php/squmj/article/view/2708

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