Cartilage Oligomeric Matrix Protein Gene Multilayers Inhibit Osteogenic Differentiation and Promote Chondrogenic Differentiation of Mesenchymal Stem Cells

Cartilage Oligomeric Matrix Protein Gene Multilayers Inhibit Osteogenic Differentiation and Promote Chondrogenic Differentiation of Mesenchymal Stem Cells

There are still many challenges to acquire the optimal integration of biomedical materials with the surrounding tissues. Gene coatings on the surface of biomaterials may offer an effective approach to solve the problem. In order to investigate the gene multilayers mediated differentiation of mesench...

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Bibliographic Details
Main Authors: Peng Guo, Zhong-Li Shi, An Liu, Tiao Lin, Fang-Gang Bi, Ming-Min Shi, Shi-Gui Yan
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:International Journal of Molecular Sciences
Subjects:
cartilage oligomeric matrix protein
layer-by-layer self-assembly
gene delivery
mesenchymal stem cells
cell differentiation
Online Access:http://www.mdpi.com/1422-0067/15/11/20117

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http://www.mdpi.com/1422-0067/15/11/20117

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