Prevalence of βS-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil

Prevalence of βS-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil

The aim of this study was to determine the frequency of beta S-globin gene (βS globin) haplotypes and alpha thalassemia with 3.7 kb deletion (−α3.7kb thalassemia) in the northwest region of Paraná state, and to investigate the oxidative and clinical-hematological profile of βS globin carriers in thi...

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Bibliographic Details
Main Authors: Eliana LitsukoTomimatsu Shimauti, Danilo Grunig Humberto Silva, Eniuce Menezes de Souza, Eduardo Alves de Almeida, Francismar Prestes Leal, Claudia Regina Bonini-Domingos
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2015-09-01
Series:Genetics and Molecular Biology
Subjects:
antioxidants
hemoglobinopathies
melatonin
sickle cell disease
thalassemia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000300316&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000300316&lng=en&tlng=en

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