Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes.

We investigated the mechanisms of excitation-contraction (EC) coupling in human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and fetal ventricular myocytes (hFVMs) using patch-clamp electrophysiology and confocal microscopy. We tested the hypothesis that Ca(2+) influx via voltage-gated L-ty...

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Bibliographic Details
Main Authors: Wei-Zhong Zhu, Luis F Santana, Michael A Laflamme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2671137?pdf=render