Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes

Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to regulate transcription through super-enhancers and...

Full description

Bibliographic Details
Main Authors: Hong Wang, Aiping Duan, Jing Zhang, Qi Wang, Yuexian Xing, Zhaohui Qin, Zhihong Liu, Jingping Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02209-8