Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection.

Chronic immune activation and progression to AIDS are observed after SIV infection in macaques but not in natural host primate species. To better understand this dichotomy, we compared acute pathogenic SIV infection in pigtailed macaques (PTs) to non-pathogenic infection in African green monkeys (AG...

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Bibliographic Details
Main Authors: David Favre, Sharon Lederer, Bittoo Kanwar, Zhong-Min Ma, Sean Proll, Zeljka Kasakow, Jeff Mold, Louise Swainson, Jason D Barbour, Carole R Baskin, Robert Palermo, Ivona Pandrea, Christopher J Miller, Michael G Katze, Joseph M McCune
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19214220/?tool=EBI