Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia.

Several cell types are considered to be effector cells in bile duct injury in rhesus rotavirus (RRV)-induced experimental biliary atresia (BA). Here, we identified an increased T helper 17 (Th17) cell population in a BA mode. By depleting the Th17 cells, the BA symptoms (onset of jaundice, acholic s...

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Bibliographic Details
Main Authors: Yong-Jun Liu, Kang Li, Li Yang, Shao-Tao Tang, Xin-Xing Wang, Guo-Qing Cao, Shuai Li, Hai-Yan Lei, Xi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4556529?pdf=render