Nintedanib in non-small cell lung cancer: from preclinical to approval

Angiogenesis is a driving force of a tumor’s development. Targeting this process is an attractive option, as this is a feature shared by most of the solid tumors. A lot of antiangiogenic drugs have been developed following this path, including bevacizumab, sorafenib, sunitinib, vandetanib, ramucirum...

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Bibliographic Details
Main Authors: Christian Caglevic, Massimiliano Grassi, Luis Raez, Angela Listi, Marco Giallombardo, Eva Bustamante, Ignacio Gil-Bazo, Christian Rolfo
Format: Article
Language:English
Published: SAGE Publishing 2015-08-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465815579608