Regulation of DNA damage repair and lipid uptake by CX3CR1 in epithelial ovarian carcinoma

Abstract Failure of currently used cytotoxic chemotherapy is one of the main reasons behind high mortality from metastatic high grade serous ovarian carcinoma. We found that high expression of a receptor for fractalkine (CX3CR1) significantly correlated with shorter survival of patients with serous...

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Bibliographic Details
Main Authors: Jia Xie, Hilal Gurler Main, Joelle D. Sacks, Goda G. Muralidhar, Maria V. Barbolina
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-018-0046-6