The molecular basis of ceramide-1-phosphate recognition by C2 domains[S]
Group IVA cytosolic phospholipase A2 (cPLA2α), which harbors an N-terminal lipid binding C2 domain and a C-terminal lipase domain, produces arachidonic acid from the sn-2 position of zwitterionic lipids such as phosphatidylcholine. The C2 domain has been shown to bind zwitterionic lipids, but more r...
Main Authors: | Katherine E. Ward, Nitin Bhardwaj, Mohsin Vora, Charles E. Chalfant, Hui Lu, Robert V. Stahelin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-03-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520419297 |
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