Contemporary Mouse Models in Glioma Research

Contemporary Mouse Models in Glioma Research

Despite advances in understanding of the molecular pathogenesis of glioma, outcomes remain dismal. Developing successful treatments for glioma requires faithful in vivo disease modeling and rigorous preclinical testing. Murine models, including xenograft, syngeneic, and genetically engineered models...

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Bibliographic Details
Main Authors: William H. Hicks, Cylaina E. Bird, Jeffrey I. Traylor, Diana D. Shi, Tarek Y. El Ahmadieh, Timothy E. Richardson, Samuel K. McBrayer, Kalil G. Abdullah
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
glioma
genetically engineered mouse models (GEMM)
isocitrate dehydrogenase (IDH)
patient-derived xenograft (PDX)
mouse model
Online Access:https://www.mdpi.com/2073-4409/10/3/712

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https://www.mdpi.com/2073-4409/10/3/712

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