AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity

In this study, we demonstrate that activation of AMP-activated protein kinase (AMPK) with glabridin alleviates adiposity and hyperlipidemia in obesity. In several obese rodent models, glabridin decreased body weight and adiposity with a concomitant reduction in fat cell size. Further, glabridin amel...

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Main Authors: Joo-Won Lee, Sung Sik Choe, Hagoon Jang, Jiyeong Kim, Hyun Woo Jeong, Hyunsun Jo, Kyeong-Hoon Jeong, Surendar Tadi, Myoung Gyu Park, Tae Hwan Kwak, Jin Man Kim, Dong-Hoon Hyun, Jae Bum Kim
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345041