Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency.

Although severe combined immune deficiency (SCID) is a very important research model for mice and SCID mice are widely used, there are only few reports describing the SCID pig models. Therefore, additional research in this area is needed. In this study, we describe the generation of Recombination ac...

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Bibliographic Details
Main Authors: Tetsuya Ito, Yutaka Sendai, Satoshi Yamazaki, Marie Seki-Soma, Kensuke Hirose, Motoo Watanabe, Kazuo Fukawa, Hiromitsu Nakauchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4249935?pdf=render