Production of the Ramoplanin Activity Analogue by Double Gene Inactivation.

Glycopeptides such as vancomycin and telavancin are essential for treating infections caused by Gram-positive bacteria. But the dwindling availability of new antibiotics and the emergence of resistant bacteria are making effective antibiotic treatment increasingly difficult. Ramoplanin, an inhibitor...

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Bibliographic Details
Main Authors: Jungang Han, Junsheng Chen, Lei Shao, Junliang Zhang, Xiaojing Dong, Pengyu Liu, Daijie Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4858212?pdf=render