Genetic Variant of C-5434T REN Enhancer on Serum Renin Levels and Binding Pattern of Signal Transducers and Activators Transcription 3

The human renin gene has been widely known to be involved in essential hypertension (EH) pathogenesis. Genetic variant C-5434T of REN enhancer contributed to renin gene transcription and serum renin regulation. However, the mechanism associated with the transcription level changes remains unknown, a...

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Bibliographic Details
Main Authors: Imama Maslahah, Mohammad Saifur Rohman, Nashi Widodo, Agustina Tri Endharti, Didik Utomo
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2015/486961