G-CSF does not influence C2C12 myogenesis despite receptor expression in healthy and dystrophic skeletal muscle

G-CSF does not influence C2C12 myogenesis despite receptor expression in healthy and dystrophic skeletal muscle

Granulocyte-colony stimulating factor (G-CSF) increases recovery of rodent skeletal muscles after injury, and increases muscle function in rodent models of neuromuscular disease. However, the mechanisms by which G-CSF mediates these effects are poorly understood. G-CSF acts by binding to the membran...

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Bibliographic Details
Main Authors: Craig Robert Wright, Erin Louise Brown, Paul A Della-Gatta, Alister C Ward, Gordon S Lynch, Aaron Paul Russell
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Physiology
Subjects:
cytokine receptor
skeletal muscle
mdx
Duchenne muscular dystrophy
G-CSF
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00170/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00170/full

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