An analysis of the global expression of microRNAs in an experimental model of physiological left ventricular hypertrophy.

BACKGROUND: MicroRNAs (miRs) are a class of small non-coding RNAs that regulate gene expression. Studies of transgenic mouse models have indicated that deregulation of a single miR can induce pathological cardiac hypertrophy and cardiac failure. The roles of miRs in the genesis of physiological left...

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Main Authors: Nidiane C Martinelli, Carolina R Cohen, Kátia G Santos, Mauro A Castro, Andréia Biolo, Luzia Frick, Daiane Silvello, Amanda Lopes, Stéfanie Schneider, Michael E Andrades, Nadine Clausell, Ursula Matte, Luis E Rohde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994002?pdf=render