Methyl-β-Cyclodextrin Impairs the Phosphorylation of the β<sub>2</sub> Subunit of L-Type Calcium Channels and Cytosolic Calcium Homeostasis in Mature Cerebellar Granule Neurons

The activation of L-type calcium channels (LTCCs) prevents cerebellar granule neurons (CGNs) from entering low-K<sup>+</sup>-induced apoptosis. In previous works, we showed that LTCCs are largely associated with caveolin-1-rich lipid rafts in the CGN plasma membrane. In this work, we sho...

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Bibliographic Details
Main Authors: Sofia Fortalezas, Dorinda Marques-da-Silva, Carlos Gutierrez-Merino
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
PKA
Online Access:https://www.mdpi.com/1422-0067/19/11/3667