The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells

The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells

γδ T cells contribute to first line immune defense, particularly through their ability for rapid production of proinflammatory cytokines. The cytokine profile of γδ T cells is hard-wired already during thymic development. Yet, the molecular pathways underlying this phenomenon are incompletely unders...

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Bibliographic Details
Main Authors: Florian Mair, Stefanie Joller, Romy Hoeppli, Lucas Onder, Matthias Hahn, Burkhard Ludewig, Ari Waisman, Burkhard Becher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
NIK
thymic stroma
γδ T cells
Immunology
T cell development
Online Access:https://elifesciences.org/articles/10087

Internet

https://elifesciences.org/articles/10087

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