Multiple links between 5-methylcytosine content of mRNA and translation

Multiple links between 5-methylcytosine content of mRNA and translation

Abstract Background 5-Methylcytosine (m5C) is a prevalent base modification in tRNA and rRNA but it also occurs more broadly in the transcriptome, including in mRNA, where it serves incompletely understood molecular functions. In pursuit of potential links of m5C with mRNA translation, we performed...

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Bibliographic Details
Main Authors: Ulrike Schumann, He-Na Zhang, Tennille Sibbritt, Anyu Pan, Attila Horvath, Simon Gross, Susan J. Clark, Li Yang, Thomas Preiss
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Biology
Subjects:
Epitranscriptome
RNA methylation
5-Methylcytosine
NSUN2
TRDMT1
Bisulfite conversion
Online Access:http://link.springer.com/article/10.1186/s12915-020-00769-5

Internet

http://link.springer.com/article/10.1186/s12915-020-00769-5

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