Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from Uganda

Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from Uganda

Abstract Background Rapid diagnostic tests (RDTs) play a key role in malaria case management. The most widely used RDT identifies Plasmodium falciparum based on immunochromatographic recognition of P. falciparum histidine-rich protein 2 (PfHRP2). Deletion of the paralogous pfhrp2 and pfhrp3 genes le...

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Bibliographic Details
Main Authors: Sam L. Nsobya, Andrew Walakira, Elizabeth Namirembe, Moses Kiggundu, Joaniter I. Nankabirwa, Emmanuel Ruhamyankaka, Emmanuel Arinaitwe, Melissa D. Conrad, Moses R. Kamya, Grant Dorsey, Philip J. Rosenthal
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Malaria Journal
Subjects:
pfhrp2
pfhrp3
Plasmodium falciparum
HRP2
Rapid diagnostic test
Online Access:https://doi.org/10.1186/s12936-020-03547-4

Internet

https://doi.org/10.1186/s12936-020-03547-4

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