The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner.

The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner.

Type 2 diabetes is typified by insulin-resistance in adipose tissue, skeletal muscle, and liver, leading to chronic hyperglycemia. Additionally, obesity and type 2 diabetes are characterized by chronic low-grade inflammation. Membrane-associated RING-CH-1 (MARCH1) is an E3 ubiquitin ligase best know...

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Bibliographic Details
Main Authors: Candida Bhagwandin, Erin L Ashbeck, Michael Whalen, Joanna Bandola-Simon, Paul A Roche, Adam Szajman, Sarah Mai Truong, Betsy C Wertheim, Yann C Klimentidis, Satoshi Ishido, Benjamin J Renquist, Lonnie Lybarger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6200199?pdf=render

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http://europepmc.org/articles/PMC6200199?pdf=render

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