A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan [version 3; peer review: 2 approved, 2 approved with reservations]

Background: The CRASH-3 trial is a randomised trial on the effect of tranexamic acid (TXA) versus placebo on death and disability in traumatic brain injury (TBI). The CRASH-3 intracranial bleeding mechanistic study (IBMS) is a randomised trial nested within the CRASH-3 trial to examine the effect of...

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Bibliographic Details
Main Authors: Abda Mahmood, Ian Roberts, Haleema Shakur-Still
Format: Article
Language:English
Published: Wellcome 2019-11-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-99/v3