The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS

Methylation of histone H3 lysine 4 (H3K4) by Set1/COMPASS occurs co-transcriptionally, and is important for gene regulation. Here the authors provide evidence that the Set1 N-terminal region and the COMPASS subunit Swd2 interact with RNA polymerase II CTD to recruit COMPASS in budding yeast.

Bibliographic Details
Main Authors: Hyun Jin Bae, Marion Dubarry, Jongcheol Jeon, Luis M. Soares, Catherine Dargemont, Jaehoon Kim, Vincent Geli, Stephen Buratowski
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16082-2