Network Analysis Reveals TNF as a Major Hub of Reactive Inflammation Following Spinal Cord Injury

Abstract Spinal cord injury (SCI) leads to reactive inflammation and other harmful events that limit spinal cord regeneration. We propose an approach for studying the mechanisms at the levels of network topology, gene ontology, signaling pathways, and disease inference. We treated inflammatory media...

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Bibliographic Details
Main Authors: Weiping Zhu, Xuning Chen, Le Ning, Kan Jin
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-37357-1