Inhibitor of the transcription factor NF-κB, DHMEQ, enhances the effect of paclitaxel on cells of anaplastic thyroid carcinoma in vitro and in vivo

Inhibitor of the transcription factor NF-κB, DHMEQ, enhances the effect of paclitaxel on cells of anaplastic thyroid carcinoma in vitro and in vivo

Anticancer drug paclitaxel (Ptx) effect on biochemical mechanisms, regulating apoptosis in anaplastic thyroid carcinoma cells, was studied. It was shown that in addition to apoptotic cell death, Ptx induces signa­ling cascades that ensure cell survival. Paclitaxel-induced activation of nuclear facto...

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Bibliographic Details
Main Authors: V. V. Pushkarev, D. V. Starenki, V. M. Pushkarev, O. I. Kovzun, M. D. Tronko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2015-06-01
Series:Ukrainian Biochemical Journal
Subjects:
anaplastic cancer
apoptosis
NF-κВ
paclitaxel
thyroid
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/07/Pushkarev_3_15.pdf

Internet

http://ukrbiochemjournal.org/wp-content/uploads/2015/07/Pushkarev_3_15.pdf

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